pmxTools: Pharmacometric and Pharmacokinetic Toolkit

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

Version: 1.3
Depends: R (≥ 3.50), patchwork
Imports: ggplot2, chron, xml2, dplyr (≥ 0.8.5), tibble, gghalves, ggdist, scales, MASS, stringr, PKNCA, magrittr, data.tree
Suggests: testthat, vdiffr, knitr, rmarkdown
Published: 2023-02-21
DOI: 10.32614/CRAN.package.pmxTools
Author: Justin Wilkins ORCID iD [aut, cre], Bill Denney ORCID iD [aut], Rik Schoemaker [aut], Satyaprakash Nayak [ctb], Leonid Gibiansky [ctb], Andrew Hooker [ctb], E. Niclas Jonsson [ctb], Mats O. Karlsson [ctb], John Johnson [ctb]
Maintainer: Justin Wilkins <justin.wilkins at>
Contact: Justin Wilkins <>
License: GPL-2
NeedsCompilation: no
Materials: README NEWS
In views: Pharmacokinetics
CRAN checks: pmxTools results


Reference manual: pmxTools.pdf
Vignettes: Drawing PK curves with pmxTools


Package source: pmxTools_1.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): pmxTools_1.3.tgz, r-oldrel (arm64): pmxTools_1.3.tgz, r-release (x86_64): pmxTools_1.3.tgz, r-oldrel (x86_64): pmxTools_1.3.tgz
Old sources: pmxTools archive

Reverse dependencies:

Reverse suggests: mrgsolve, PKNCA


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