HMC: High-Dimensional Mean Comparison with Projection and Cross-Fitting

Provides interpretable high-dimensional mean comparison methods (HMC). For example, users can apply these methods to assess the difference in gene expression between two treatment groups. It is not a gene-by-gene comparison. Instead, the methods focus on the interplay between features and identify those that are predictive of the group label. The tests are valid frequentist procedures and yield sparse estimates indicating which features contribute to the group differences.

Version: 1.2
Imports: glmnet, irlba, PMA, MASS, stats, grpreg
Published: 2025-05-02
Author: Tianyu Zhang [aut, cre, cph]
Maintainer: Tianyu Zhang <tianyuz3 at andrew.cmu.edu>
License: GPL-2
URL: https://github.com/terrytianyuzhang/HMC/tree/main/HMC_package
NeedsCompilation: no
CRAN checks: HMC results

Documentation:

Reference manual: HMC.pdf

Downloads:

Package source: HMC_1.2.tar.gz
Windows binaries: r-devel: HMC_1.1.zip, r-release: HMC_1.1.zip, r-oldrel: HMC_1.1.zip
macOS binaries: r-release (arm64): HMC_1.1.tgz, r-oldrel (arm64): HMC_1.1.tgz, r-release (x86_64): HMC_1.1.tgz, r-oldrel (x86_64): HMC_1.1.tgz
Old sources: HMC archive

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