GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing
Studies, Either Single SNP Tests or Region-Based Tests
The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
||ChangJiang Xu and Celia M.T. Greenwood
||ChangJiang Xu <changjiang.h.xu at gmail.com>
||GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
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