2014/02/08 Sebastien Bihorel * Change vignette data location to comply to R 3.0 requirements * Add NAMESPACE * Minor modification to accommodate upgrade in neldermead packages * Added protection of parameter variables so they cannot be modified in $DERIVED * Deprecated functions: zzz.R 2011/12/10 Sebastien Bihorel * Switch from dde function (PBSddesolve package) to dede function (deSolve package) to integrate of delayed differential equations. Dependency to * Change in input arguments to scarabee.new due to the switch in the dede solver. * Bug fixes in making.dosing.R, ode.model.R, and dde.model.R to correct problem with dosing history. * Deprecated functions: dde.map, dde.switch, and get.switch.vector. 2011/04/12 Sebastien Bihorel * Windows-specific bugs in demos have been corrected * Vignette updated to document the demos. 2011/03/31 Sebastien Bihorel * scaRabee gets a major overhaul with version 1.1. Changes affect almost every provided functionalities. * scaRabee now reads (only) datasets specified using NONMEM or S-ADPAT standards. Dosing and covariates files are no longer required and multiple functions have been modified accordingly. * scaRabee model is now specified in a single txt file, which uses a tag-based syntax, very much like the one used in NM-TRAN control streams, S-ADAPT-TRAN models, or MONOLIX models. Residual variability and secondary parameters are also specified in the same file. * scaRabee now can perform population analysis using the standard two stage method. * scaRabee now can perform direct grid search. * There is no backward compatibility with versions 1.0. * Almost all existing functions were modified as a result of these changes. New functions are distributed with version 1.1. * init.report was given a new name initialize.report * Deprecated functions: find.id.R and weigthing.additive 2010/07/30 Sebastien Bihorel * scarabee.analysis: corrected data file reading issues when observations are provided for more than one system states. * estimation.plot and simulation.plot: move the par(ask=TRUE) call * find.id: modify code to allow user to specify its own 2010/05/25 Sebastien Bihorel * DESCRIPTION: added missing dependencies to deSolve and PBSddesolve packages * scarabee.directory: corrected permission problems in Windows environment in all file.copy calls. 2010/05/11 Sebastien Bihorel * scaRabee.Rnw: corrected \bibliography{scaRabee.bib} to \bibliography{scaRabee} to address compilation issue in Windows.