lit: Latent Interaction Testing for Genome-Wide Studies

Identifying latent genetic interactions in genome-wide association studies using the Latent Interaction Testing (LIT) framework. LIT is a flexible kernel-based approach that leverages information across multiple traits to detect latent genetic interactions without specifying or observing the interacting variable (e.g., environment). LIT accepts standard PLINK files as inputs to analyze large genome-wide association studies.

Version: 1.0.0
Imports: Rcpp (≥ 1.0.11), genio, CompQuadForm
LinkingTo: Rcpp, RcppArmadillo, RcppEigen
Suggests: testthat (≥ 3.0.0), knitr, rmarkdown
Published: 2023-08-15
DOI: 10.32614/CRAN.package.lit
Author: Andrew Bass [aut, cre], Michael Epstein [aut]
Maintainer: Andrew Bass <ajbass at>
License: LGPL-2 | LGPL-2.1 | LGPL-3 [expanded from: LGPL]
NeedsCompilation: yes
Materials: README NEWS
CRAN checks: lit results


Reference manual: lit.pdf
Vignettes: LIT: Latent Interaction Testing


Package source: lit_1.0.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): lit_1.0.0.tgz, r-oldrel (arm64): lit_1.0.0.tgz, r-release (x86_64): lit_1.0.0.tgz, r-oldrel (x86_64): lit_1.0.0.tgz


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