## ----eval=FALSE--------------------------------------------------------------- # # residual error and bio-availability can be added in the des_func e.g. # CP <- (A2/V) * F1 * (1 + rnorm(length(A2),0,sqrt(0.01))) # # lag time should be adapted in the events data frame e.g. # events <- dose_func(cmt=1,value=300,ndose=3,tau=24) # events$time <- events$time + pars['TLAG'] # # infusions should be handled in the event and are supported in dose_func # # see template models how this can be adapted in the model part (?tmpl_model) # dose_func(cmt=4,value=300,ndose=3,tau=24, tinf=2)