MRTAnalysis

The MRTAnalysis package provides functions to conduct post-study analyses of Micro-Randomized Trials (MRTs), focusing on estimating causal excursion effects.

• Proximal outcomes (measured shortly after each treatment decision point):
  • wcls(): Primary analysis for continuous proximal outcomes. Implements weighted and centered least squares (the \(k=1\) special case of Boruvka et al., 2018).
  • emee(): Primary analysis for binary proximal outcomes. Implements the estimator for marginal excursion effect (the \(\Delta=1\) special case of Qian et al., 2021).
  • emee2(): Variant of emee(), centering treatment in the residual term. Basis for the sample size calculator in MRTSampleSizeBinary.
• Distal outcomes (measured once at end of study):
  • dcee(): Exploratory analysis for distal causal excursion effects in MRTs (Qian et al. 2025). Supports linear models and machine-learning learners (lm, gam, random forest, ranger, SuperLearner) with optional cross-fitting.

Installation

You can install the package from CRAN:

install.packages("MRTAnalysis")

Usage

See vignettes for detailed examples:

library(MRTAnalysis)

# Proximal outcome analysis (continuous)
fit1 <- wcls(
  data = data_mimicHeartSteps,
  id = "userid", outcome = "logstep_30min",
  treatment = "intervention", rand_prob = 0.6,
  moderator_formula = ~1,
  control_formula = ~logstep_pre30min,
  availability = "avail"
)
summary(fit1)

# Distal outcome analysis
fit2 <- dcee(
  data = data_distal_continuous,
  id = "userid", outcome = "Y",
  treatment = "A", rand_prob = "prob_A",
  moderator_formula = ~1,
  control_formula = ~X,
  availability = "avail",
  control_reg_method = "lm"
)
summary(fit2)

References

• Boruvka, A., Almirall, D., Witkiewitz, K., & Murphy, S. A. (2018). Assessing time-varying causal effect moderation in mobile health. Journal of the American Statistical Association, 113(523), 1112–1121. doi:10.1080/01621459.2017.1305274

• Qian, T., Yoo, H., Klasnja, P., Almirall, D., & Murphy, S. A. (2021). Estimating time-varying causal excursion effects in mobile health with binary outcomes. Biometrika, 108(3), 507–527. doi:10.1093/biomet/asaa070

• Qian, T. (2025). Distal Causal Excursion Effects: Modeling Long-Term Effects of Time-Varying Treatments in Micro-Randomized Trials. arXiv:2502.13500.