Type: Package
Title: Diagnosis of Metabolic Dysfunction Associated Fatty Liver Disease
Version: 3.0.0
Description: The latest guidelines proposed by International Expert Consensus are used for the clinical diagnosis of Metabolic Associated Fatty Liver Disease (MAFLD). The new definition takes hepatic steatosis (determined by elastography or histology or biomarker-based fatty liver index) as a major criterion. In addition, race, gender, body mass index (BMI), waist circumference (WC), fasting plasma glucose (FPG), systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), high-density lipoprotein cholesterol (HDLC), homeostatic model assessment of insulin resistance (HOMAIR), high sensitive c-reactive protein (HsCRP) for the diagnosis of MAFLD. Each parameter has to be interpreted based on the proposed cut-offs, making the diagnosis slightly complex and error-prone. This package is developed by incorporating the latest international expert consensus guidelines, and it will aid in the easy and quick diagnosis of MAFLD based on FibroScan in busy healthcare settings and also for research purposes. The new definition for MAFLD as per the International Consensus Statement is described by Eslam M et al (2020). <doi:10.1016/j.jhep.2020.03.039>.
License: GPL (≥ 3)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
URL: https://github.com/jagadishramasamy/mafld
BugReports: https://github.com/jagadishramasamy/mafld/issues
Suggests: knitr, rmarkdown, testthat
Imports: dplyr
Depends: R (≥ 3.5.0)
NeedsCompilation: no
Packaged: 2025-09-09 15:43:27 UTC; jagadish
Author: Jagadish Ramasamy ORCID iD [aut, cre]
Maintainer: Jagadish Ramasamy <iamjagankmr@gmail.com>
Repository: CRAN
Date/Publication: 2025-09-14 16:10:13 UTC

Diagnosis of Metabolic Dysfunction Associated Fatty Liver Disease

Description

The latest guidelines proposed by International Expert Consensus are used widely for the clinical diagnosis of Metabolic Associated Fatty Liver Disease (MAFLD). The new definition takes hepatic steatosis (determined by elastography or histology or biomarker-based fatty liver index) as a major criterion. In addition, race, gender, body mass index (BMI), waist circumference (WC), fasting plasma glucose (FPG), systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), high-density lipoprotein cholesterol (HDLC), homeostatic model assessment of insulin resistance (HOMAIR), high sensitive c-reactive protein (HsCRP) for the diagnosis of MAFLD. Each parameter has to be interpreted based on the proposed cut-offs, making the diagnosis slightly complex and error-prone. This package is developed by incorporating the latest international expert consensus guidelines, and it will aid in the easy and quick diagnosis of MAFLD based on FibroScan in busy healthcare settings and also for research purposes. The new definition for MAFLD as per the International Consensus Statement is described by Eslam M et al (2020). <doi:10.1016/j.jhep.2020.03.039>.

Usage

MAFLD(x)

Arguments

x

a data frame with column names as exactly specified.

Value

Yes or No

Examples

MAFLD(x)

An example data frame

Description

A data frame with exact column names as specified

Usage

x

Format

A data frame with parameters needed to diagnose MAFLD:

CAP

Controlled Attenuation Parameter in dB/m

BMI

Body mass index in kg/m2

Race

either Caucasians or Asians

Gender

Gender in Male or Female

WC

Waist Circumference in cm

FPG

Fasting plasma glucose in mg/dL

HbA1C

Glycated Hemoglobin (in%)

SBP

Systolic BP in mm Hg

DBP

Diastolic BP in mm Hg

HDL

High Density Lipoprotein Cholesterol in mg/dL

TG

Triglycerides in mg/dL

HOMAIR

Homeostatis Model Assessment of Inuslin Resistance

HSCRP

High Sensitive C reative Protein