--- title: "Trajectories Tab" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Trajectories Tab} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ``` ## Introduction The **Trajectories** tab compares concept ordering patterns across clusters using median occurrence timing and prevalence. To illustrate the timing data behind this tab, the next chunk extracts the first recorded event day for each concept occurrence and summarizes the most common concepts in the bundled `lc500` study. ```{r} if (requireNamespace("nanoparquet", quietly = TRUE)) { studyDir <- system.file("example", "st", package = "CohortContrast") study <- CohortContrast::loadCohortContrastStudy("lc500", pathToResults = studyDir) firstEventDay <- function(x) { values <- strsplit(as.character(x), ",")[[1]] as.numeric(trimws(values[1])) } patientData <- study$data_patients patientData$FIRST_TIME_TO_EVENT <- vapply( patientData$TIME_TO_EVENT, firstEventDay, numeric(1) ) conceptCounts <- sort(table(patientData$CONCEPT_NAME), decreasing = TRUE) topConcepts <- names(conceptCounts)[1:5] trajectoryPreview <- patientData[patientData$CONCEPT_NAME %in% topConcepts, ] aggregate( FIRST_TIME_TO_EVENT ~ CONCEPT_NAME, data = trajectoryPreview, FUN = median ) } ``` This is a simplified version of the temporal information the Trajectories tab uses for concept ordering comparisons across clusters. ![Trajectories tab](../man/figures/a04_trajectories.png) ## Controls - **Row ordering**: - `Overall order`: ranked by overall timing. - `Top movers`: emphasizes concepts whose ordering shifts most across clusters. - `Most stable`: emphasizes concepts with minimal ordering drift. - **Cluster Prevalence (%)** (sidebar): when a specific cluster is selected, filters concepts by minimum within-cluster prevalence. ## Interpretation - Concepts that move strongly between clusters can indicate cluster-defining care pathways. - Concepts with stable ordering are useful anchors for comparing trajectories across cohorts/studies. - Use this tab together with **Dashboard**: keep only clinically relevant concepts active, then inspect temporal ordering stability.