# Goldilocks Adaptive Trial Designs for Time-to-Event Endpoints

## Documentation for package ‘goldilocks’ version 0.5.0

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

enrollment | Simulate enrollment times
goldilocks | goldilocks
ppwe | Cumulative distribution function of the PWE for a vectorized hazard rate parameter
prop_to_haz | Estimate plausible piecewise constant hazard rates from summary summary event proportions
pwe_impute | Impute piecewise exponential time-to-event outcomes
pwe_sim | Simulate piecewise exponential time-to-event outcomes
randomization | Randomization allocation
sim_comp_data | Simulate a complete clinical trial with event data drawn from a piecewise exponential distribution
sim_trials | Simulate one or more clinical trials subject to known design parameters and treatment effect
summarise_sims | Summarize simulations to get operating characteristics
survival_adapt | Simulate and execute a single adaptive clinical trial design with a time-to-event endpoint