In-Silico Knockout Experiments from Single-Cell Gene Regulatory Networks


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Documentation for package ‘scTenifoldKnk’ version 2.0.0

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dRegulation Evaluates gene differential regulation based on manifold alignment distances.
heatKernel Spectral heat kernel of a gene-gene matrix
hkManifoldAlignment Heat-kernel (hk) manifold alignment for in-silico knockouts
knockoutDirection Direction of the response to an in-silico knockout
perturbationMap Map of transcriptome-wide perturbation profiles
plotKO Plot KO network
scQC Performs single-cell data quality control
scTenifoldKnk scTenifoldKNK