Dose Transition Pathways for Time-to-Event Dose-Finding Designs

Documentation for package ‘dtptite’ version 0.1.0

apply_dtp	Apply the DTP look-ahead to a TITE selector factory.
dtp_projected_dose	Projected dose after waiting.
dtp_should_wait	Should the trialist wait before dosing the next cohort?
dtp_wait_events	Raw DTP wait event log from simulated trials.
dtp_wait_summary	Per-trial DTP wait summary from simulated trials.
dtp_wait_time	Minimum wait time before the dose recommendation changes.
get_boin_tite	Create a TITE-BOIN dose-finding selector.
plot.time_to_first_mtd	Plot the cumulative incidence of reaching the MTD.
scenario_mtd	True MTD of a simulated scenario.
set_dtp_queue_size	Set the waiting-room capacity for DTP simulation.
stop_for_beta_binomial_toxicity	Stop for excessive toxicity using a Beta-Binomial conjugate posterior.
summary.time_to_first_mtd	Summarise time-to-first-MTD across replicates.
time_to_first_mtd	Time until the first patient is dosed at the true MTD.
tite_patient_samples	Create patient samples with realistic TITE DLT timing.